Hoxworth is issuing an emergency appeal for donations. The center says its blood supplies are critically low.
Spokeswoman Alecia Lipton says all blood types are needed.
"We have seen a decline in blood donations," says Lipton. "Some of that has been caused by the flu, a little because of the weather and school cancelations, but mostly we've seen donor apathy. People just thinking, 'Oh, I'll do it later.' We've really been hit negatively with that for about the past month."